SILDENAFIL POWDER 100G

NOT FOR CONSUMPTION, FOR SCIENTIFIC RESEARCH ONLY

Sildenafil, marketed under the brand name Viagra among others, has revolutionized the treatment of erectile dysfunction (ED) since its introduction in the late 1990s. This medication, initially developed for cardiovascular conditions, has transformed the lives of millions of men worldwide. In the text below we provide you with information regarding the history of Sildenafil, the mechanism of action, uses, and safety considerations.
Sildenafil was originally synthesized by a group of pharmaceutical chemists working at Pfizer's research facility in Kent, England. Initially studied as a potential treatment for hypertension and angina pectoris, researchers quickly discovered its remarkable effects on penile erection during clinical trial.
Sildenafil belongs to a class of medications known as phosphodiesterase type 5 (PDE5) inhibitors. It works by inhibiting the enzyme PDE5, which regulates blood flow in the penis. By blocking PDE5, Sildenafil enhances the natural process of arousal, allowing for increased blood flow to the penis when sexually stimulated. This leads to firmer and longer-lasting erections, helping men with ED achieve and maintain satisfactory sexual activity.
The primary indication for Sildenafil is the treatment of erectile weakness or dysfunction. Clinical trials have demonstrated the efficacy of sildenafil in improving erectile function across a wide range of underlying causes, including vascular, neurogenic, psychological, and hormonal factors.
Additionally, Sildenafil has been investigated for other off-label uses, such as the treatment of pulmonary arterial hypertension (PAH). In this context, sildenafil works by dilating the blood vessels in the lungs, reducing pulmonary blood pressure and improving exercise capacity in patients with PAH.